实验室新闻

    科研进展

    实验室公告

    学术活动公告

 
[CARBON]Enhanced antibacterial activity of magnetic biochar conjugated quaternary phosphonium salt
 点击数:79次 添加时间:  [关闭] [收藏]

作者:Fu, YH (Fu, Yuhao); Wang, F (Wang, Fang) ; Sheng, HJ (Sheng, Hongjie) ; Xu, M (Xu, Min) ; Liang, Y (Liang, Ying); Bian, YR (Bian, Yongrong) ; Hashsham, SA (Hashsham, Syed A.); Jiang, X (Jiang, Xin) ; Tiedje, JM (Tiedje, James M.)

 

题目:Enhanced antibacterial activity of magnetic biochar conjugated quaternary phosphonium salt

 

刊物:CARBON,卷: 163 页: 360-369

DOI: 10.1016/j.carbon.2020.03.010

出版年: AUG 15 2020

 

文章链接:https://www.sciencedirect.com/science/article/pii/S0008622320302530?via%3Dihub

 

摘要:

Microbial contamination in water remains a global issue in threatening human health. Although current disinfection methods can effectively control microbial contamination, the formation of harmful disinfection byproducts is increasingly questioned. Towards this goal, a facile, green and low-priced bacteriocide - magnetic biochar/quaternary phosphonium salt (MBQ) - was developed using precipitation of iron oxide on biochar followed by ion exchange with quaternary phosphonium salt (QPS). Gram-negative bacteria Escherichia coli and Gram-positive bacteria Staphylococcus aureus - were used as model pathogens to quantify the antibacterial activity and to elucidate the antibacterial mechanism. MBQ was an effective antimicrobial agent against both pathogenic bacteria. The controllable release of QPS and magnetic recovery of MBQ favored antibacterial reuse. Significant disruption of membrane led to the inactivation of bacteria, resulting from the loss of cell membrane integrity and permeability. The induced oxidative damage inhibited the essential cell metabolism. Penetration of MBQ nanoparticles through the cell wall and membrane into the cytoplasm enhanced the biocide effect. Taken together, MBQ, presenting effective, recyclable and long-acting antibacterial properties, has a promising application in bacterial decontamination. (C) 2020 Elsevier Ltd. All rights reserved.

 

 

 

 

 

 

 


 

版权所有:中国科学院南京土壤研究所 苏ICP备05004320号 地 址:江苏省南京市北京东路71号 邮编:210008 网站管理